E-Scab Bar 75 gm – Indications and Usage

Indications

E-Scab Bar 75 gm cream is indicated for the treatment of scabies and crab lice infestations (Pediculosis). Scabies can affect all family members; if one person is infected, the entire household should be treated simultaneously.

Therapeutic Class

Parasiticidal preparation of  E-Scab Bar 75 gm cream

Pharmacology

The active ingredient in this E-Scab Bar 75 gm cream induces electrochemical changes across excitable cell membranes, causing sensory hyperexcitability and paralysis of pests. In mammals, it is rapidly metabolized by ester hydrolysis and excreted mainly in the urine. Metabolites can be detected within hours and persist at very low levels up to 28 days after full-body application.

Dosage

• Adults and children over 12 years: full tube

• 6–12 years: up to ½ tube

• 1–5 years: up to ¼ tube

• 2 months–1 year: up to ⅛ tube

• Under 2 months: dose not established

Administration

Before applying the cream, ensure the skin is clean, cool, and dry. Avoid hot showers or baths beforehand.

• Adults and children over 2 years: Apply from neck down, including all areas such as between fingers and toes, under nails, and soles of feet.

• Infants under 2 years: Apply to face, neck, ears, and scalp, avoiding eyes and mouth.
  Leave on for at least 8 hours, washing off afterward. Reapply to areas washed during the treatment period. Repeat after 7 days if recommended by a doctor.

Interactions

Avoid corticosteroids before treatment, as they may reduce immune response and worsen infestation.

Contraindications

Do not use in patients with known hypersensitivity to pyrethroids or any component of the cream. Nursing staff may wear gloves to prevent irritation.

Side Effects

Some individuals may experience burning, stinging, or tingling. Transient irritation, redness, edema, eczema, rash, or itching can occur.

Pregnancy & Lactation

Limited data suggest minimal risk to the fetus. Systemic absorption is extremely low, and toxicity is minimal. Use during pregnancy is generally not recommended. Safety during breastfeeding is unknown; avoid use in nursing mothers.

Precautions & Warnings

Temporary worsening of itching, redness, or swelling may occur. Avoid contact with eyes; rinse immediately with water if contact occurs.

Overdose

No reports of overdose; excessive application may cause localized irritation or more severe skin reactions.

Storage

Store in a cool, dry place, away from light, and out of reach of children.

Mode of Action

The cream contains a pyrethroid that disrupts sodium channels in pest nerve cells, causing delayed repolarization and paralysis. Less than 0.5% is absorbed topically; metabolites are excreted in urine after hepatic metabolism.